Note: Even if you are running the 64-bit Windows 10 version, you need to use a 32-bit DWORD as the value type. If you don't have such a value, then just create it.

If you need to change this option with a Registry tweak, here is how it can be done. To disable scrolling inactive windows in Windows 10, do the following. If you are not happy with the default scroll behavior of Windows 10, here is how to change it. If it is a user interface or input form with a combo box (dropdown list), accidental scrolling could change some option. Others do not like it when they inadvertently scroll an inactive window's contents which is open in the background. Some people find this feature very useful. The focus will not change and remain in the current active window.

For example, if you have an inactive Notepad window with some text, that text will be scrolled. The contents of the inactive window will be scrolled. One of the native features of Windows 10 is the ability to scroll inactive windows by just hovering over such a window with the mouse pointer and then using the mouse wheel.